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Mechanical response to potential advanced glycation end-product (AGE) inhibitors. Frozen-dead bovine cartilage explants incubated for 6 days and treated with 100 mM ribose and 500 μM resveratrol, 500 μM curcumin, or 20 mM eugenol. Data are presented as mean ± 95% confidence interval for (a) AGE crosslinks, (b) equilibrium modulus, and (c) permeability. *Versus control, #versus 100 mM ribose condition (P < 0.05).
