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. 2021 Aug 13;8(1):56–65. doi: 10.1002/osp4.545

TABLE 2.

Effects of donor FMT on inflammatory gene expression in visceral adipose tissue

Marker FMT group Control group p
MCP‐1 0.63 [0.42–0.84] 0.61 [0.37–0.84] 0.804
CD11b 1.82 [1.06–2.77] 0.85 [0.49–1.63] 0.068
CD68 0.51 [0.37–0.78] 0.40 [0.36–0.48] 0.809
Adiponectin 0.24 [0.22–0.52] 0.37 [0.21–0.45] 0.441
Leptin 0.53 [0.27–0.88] 0.26 [0.15–0.40] 0.139

Note: Expression of inflammatory genes in visceral adipose tissue, measured using qPCR, in the donor FMT group (n = 8) versus matched controls (n = 16). Expression was normalized for expression of a housekeeping gene (36B4) and expressed as arbitrary units. p values were calculated using Kolmogorov–Smirnov Z tests. Data are median (IQR).

Abbreviations: CD, cluster of differentiation; FMT, fecal microbiota transplantation; IQR, interquartile range; MCP, monocyte chemoattractant protein; qPCR, quantitative polymerase chain reaction.