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. 2022 Jan 7;12:756606. doi: 10.3389/fimmu.2021.756606

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Copyright © 2022 Wang, Mo, Tan, Wen, Dai, Zhang, Zhang, Feng, Liang, Song and Cheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Biofunction prediction based on bulk RNA-Seq analysis and single-cell analysis. (A) The GO and KEGG enrichment analysis based on the GSVA algorithm. (B) The GO enrichment analysis based on the GSEA algorithm. (C) The cell components of single cell RNA-seq analysis. (D) The distribution of ALDH2, ALDH16A1, ALDH3B1, ALDH5A1, ALDH3A1 and risk in different cell components. The AUC score of three pathways, including T cell mediated immunity (E), positive regulation of cell cycle arrest (F) and extracellular matrix disassembly (G), from the GO enrichment analysis were calculated. (H) The GO enrichment analysis based on single-cell analysis.