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. 2022 Jan 18;8:781333. doi: 10.3389/fnut.2021.781333

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Copyright © 2022 Cai, Li, Jin, Zhang, Xu, Liang, Weng, Yu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Forest plot of the meta-analysis on the effects of vitamin supplements on H. pylori eradication rate (n1: number of eradication regimen plus vitamin supplement group; n2: number of eradication regimen group); For the per-protocol analysis, combining antioxidant vitamin supplementation with the standard therapy increased the H. pylori eradication rate (RR = 1.22; 95% CI: 1.02–1.44; P < 0.001; I² = 81.0%); For the intention-to-treat analysis, antioxidant vitamins supplementation increased the H. pylori eradication rate (RR = 1.25; 95%CI: 1.06–1.47; P < 0.001; I² = 75.1%).