Table 3.
Basic characteristics of studies comparing serum vitamin levels before and after H. pylori eradication therapy.
| Study | Year | Area | Design | Age | No. before eradication (male/female) | No. after eradication (male/female) | Test time after eradication | Quality |
|---|---|---|---|---|---|---|---|---|
| Vitamin B 12 | ||||||||
| Kaptan et al. (13) | 2000 | Turkey | Case series | Mean 59.5 y | 31 (19/12) | 31 (19/12) | 3 or 6 m | 8* |
| Serin et al. (60) | 2002 | Turkey | Case series | Mean 43 y | 65 (N/A) | 65 (N/A) | 2–3 m | 7* |
| Ozer et al. (61) | 2005 | Turkey | Case series | Mean 41 y | 41 (N/A) | 41 (N/A) | 1 m | 7* |
| Marino et al. (14) | 2007 | Brazil | Case series | Mean 72.8 y | 59 (N/A) | 59 (N/A) | 6 m / 12 m | 7* |
| Folate | ||||||||
| Kaptan et al. (13) | 2000 | Turkey | Case series | Mean 59.5 y | 31 (19/12) | 31 (19/12) | 3 or 6 m | 8* |
| Ozer et al. (61) | 2005 | Turkey | Case series | Mean 41 y | 41 (N/A) | 41 (N/A) | 1 m | 7* |
| Vitamin C | ||||||||
| Banerjee et al. (28) | 1994 | UK | Case series | N/A | 11 (N/A) | 11 (N/A) | 1 m / 6 m | 7* |
| Annibale et al. (29) | 2003 | Italy | Case series | Median 47 y | 5 (N/A) | 5 (N/A) | 6 m | 7* |
N/A, not available; y, years; m, months;
*
The “star system” of the Newcastle–Ottawa scale.