Table 4.
Basic characteristics of studies focusing on the effect of vitamin supplementation on H. pylori eradication rate.
| Study | Year | Area | Design | Age of group 1 | No. of group 1 (male/female) | Age of group 2 | No. of group 2 (male/female) | Type of vitamin supplementation | Method of HP eradication |
|---|---|---|---|---|---|---|---|---|---|
| Chuang et al. (62) | 2002 | China | RCT | Mean 37.9 y | 55 (21/34) | Mean 35.6 y | 49 (19/30) | Vitamin C plus Vitamin E | Triple therapy |
| Everett et al. (63) | 2002 | UK | RCT | Mean 52 y | 29 (17/12) | Mean 49 y | 30 (16/14) | Vitamin C plus Vitamin E | Triple therapy |
| Sezikli et al. (15) | 2009 | Turkey | RCT | Mean 43 y | 80 (24/56) | Mean 44 y | 80 (28/52) | Vitamin C plus Vitamin E | Quadruple therapy |
| Sezikli et al. (64) | 2011 | Turkey | RCT | Mean 42 y | 80 (25/55) | Mean 43 y | 40 (15/25) | Vitamin C plus Vitamin E | Triple therapy |
| Sezikli et al. (65) | 2012 | Turkey | RCT | Mean 39.7 | 160 (53/107) | Mean 42.7 | 40 (13/27) | Vitamin C plus Vitamin E | Triple therapy |
| Demirci et al. (66) | 2015 | Turkey | RCT | Mean 40 y | 100 (59/41) | Mean 41 y | 100 (53/47) | Vitamin C plus Vitamin E | Triple therapy / Quadruple therapy |
| Kockar et al. (67) | 2001 | Turkey | RCT | Mean 40.0 y | 30 (N/A) | Mean 38.9 y | 30 (N/A) | Vitamin C / Vitamin A |
Triple therapy |
| Chuang et al. (68) | 2007 | China | RCT | Mean 53.2 y | 61 (N/A) | Mean 49.9 y | 55 (N/A) | Vitamin C | Triple therapy |
| Zojaji et al. (16) | 2009 | Iran | RCT | Mean 43 y | 150 (N/A) | Mean 45 y | 162 (N/A) | Vitamin C | Triple therapy |
| Kaboli et al. (69) | 2009 | Iran | Cohort | N/A | 114 (N/A) | N/A | 100 (N/A) | Vitamin C | Triple therapy |
Group 1: antibiotic + vitamin groups.
Group 2: antibiotic groups.
RCT, random controlled trial; N/A, not available; y, years; UK, United Kingdom.