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. 2022 Jan 21;23(3):87. doi: 10.3892/ol.2022.13207

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Copyright: © Hishida et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — SAM plot for significant miRNA discovery and selected miRNAs for validation. Upregulated miRNAs are shown in red and downregulated miRNAs are shown in green. Top significant miRNAs are miRNAs with smallest q-values (18) in SAM. miRNAs/miRs, microRNA; SAM, significance analysis of microarrays; CRC, colorectal cancer; SE-miRNAs in CRC, super-enhancer-associated miRNAs in colorectal cancer (23).