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Akt activation and autophagy induction on day 35 of pregnancy following local intrauterine AMD3100 infusion. Akt (S473) activation in intercaruncle and caruncle tissue (A). Endometrial autophagy induction, as demonstrated by quantification of LC3B-II abundance (B). Each graph represents the mean ± SEM and is followed by representative immunoblot. Analysis by Student’s t-test; significance determined at P < 0.05 (*).
