Fig. 3.

Differential expression of RNAs in CORT-induced PC12 cells by EES treatment. Volcano plots (A and B) were used to visualize the differential expression between NC versus Model groups, and EES versus Model groups severally. X-axis: Log2-fold change of RNA expression levels. Y-axis: q-value (−log10 transformed, adjusted p-value) of the RNA. The Venn diagram (C) summarizes comparably and differentially expressed genes, whereas the heat map (D and E) provides a global view of differentially expressed genes. Colors correspond to significant fold change expression. Red, high expression; blue, low expression