Table 1.

Clinical goals used in the TPS RayStation for VMAT plan generation

Function	ROI	Description	Weight
Max dose	Rectum	74 Gy	0.03
Max EUD, A = 12	Rectum	64 Gy	0.11
Max EUD, A = 8	Bladder	63 Gy	0.03
Min dose	PTV	74 Gy	0.42
Uniform dose	PTV	74 Gy	0.07
Max dose	PTV	77.7 Gy	0.21
Dose fall-off	External	[H]74 Gy, [L] 10 Gy,	0.13
		Low dose distance 1 cm

For each region of interest (ROI) a given objective function was assigned. Weights were normalized to 1 and indicate the importance of each parameter during plan optimization