Table 2.
Longitudinal parameters of 168 participants at baseline and follow-up visits
| Parameterc,d | Baseline | One-year follow-up | Two-year follow-up | ΔThickness | F | P |
|---|---|---|---|---|---|---|
| SER (D) | − 2.39 (− 2.75, − 2.00) | − 3.41 (− 4.00, − 2.87) | − 3.88 (− 4.50, − 3.25) | – | 798.16 | < 0.001 |
| AL (mm) | 24.58 (24.04, 25.08) | 24.94 (24.43, 25.44) | 25.24 (24.71, 25.71) | – | 1113.87 | < 0.001 |
| Retina (µm) | 251.12 ± 15.91a | 251.09 ± 16.34b | 253.47 ± 15.74a,b | – | 23.785 | < 0.001 |
| RNFL (µm) | 14.47 ± 1.96a | 14.93 ± 2.23a,b | 14.31 ± 2.31a | – | 3.652 | 0.027 |
| GCL + IPL (µm) | 24.34 ± 5.96 | 24.31 ± 5.85 | 24.63 ± 6.07 | – | 1.407 | 0.352 |
| HFL + ONL (µm) | 88.29 ± 10.67a,b | 90.74 ± 10.92a | 90.16 ± 10.49b | – | 10.262 | < 0.001 |
| Choroid (µm) | ||||||
| Central | 231.03 ± 54.04 | 223.71 ± 56.76 | 206.53 ± 59.71 | 24.63 ± 31.16 | 66.635 | < 0.001 |
| Para-N | 197.44 ± 55.73 | 190.25 ± 57.16 | 175.36 ± 61.67 | 22.08 ± 26.61 | 81.990 | < 0.001 |
| Para-T | 241.78 ± 53.88 | 229.81 ± 53.11 | 216.47 ± 60.57 | 24.30 ± 33.89 | 58.673 | < 0.001 |
| Para-S | 233.09 ± 50.10 | 228.39 ± 54.66 | 214.97 ± 56.65 | 18.11 ± 34.06 | 32.074 | < 0.001 |
| Para-I | 236.17 ± 54.42 | 228.91 ± 58.02 | 212.57 ± 61.23 | 23.59 ± 32.39 | 59.813 | < 0.001 |
| Peri-N | 155.47 ± 49.74 | 152.75 ± 50.89 | 139.12 ± 52.79 | 16.35 ± 22.65 | 61.377 | < 0.001 |
| Peri-T | 244.04 ± 53.80 | 234.45 ± 52.27 | 221.23 ± 60.11 | 22.81 ± 38.93 | 38.841 | < 0.001 |
| Peri-S | 232.69 ± 51.47 | 231.60 ± 52.17 | 221.48 ± 56.13 | 11.20 ± 38.41 | 11.048 | < 0.001 |
| Peri-I | 229.81 ± 53.64 | 224.72 ± 54.80 | 212.03 ± 59.96 | 17.77 ± 31.45 | 35.879 | < 0.001 |
ΔThickness, change in choroidal thickness between the baseline and the 2-year follow-up
SER= spherical equivalent of refraction; D= dioptre; AL= axial length; RNFL= retinal nerve fibre layer; GCL + IPL= ganglion cell layer and inner plexiform layer; HFL + ONL= Henle fibre layer and outer nuclear layer; Para= parafoveal; Peri= perifoveal; N= nasal; T= temporal; S= superior; I= inferior
a,bThe same superscript letter indicate a significant difference between the two results after pairwise comparison using Bonferroni correction
cMedians (interquartile range) for SER and AL
dThe means ± standard deviations for RNFL, GCL + IPL, HFL + ONL, retina, and choroid