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. 2021 Nov 19;9(2):2102678. doi: 10.1002/advs.202102678

Figure 8.

Figure 8

MBGs application for anticancer drug delivery in vivo. A) Schematic illustration of MBG nanosphere functionalization mechanism and drug loading and drug‐loaded MBG effect on tumor size. B) In vivo antitumor efficacy of dendritic MBG nanospheres in a mouse tumor xenograft model. Mice were injected with saline, mesoporous silica nanoparticles (MSN), dendritic MBG, DOX–MSN, DOX–MBG, and free DOX. Image shows the solid tumors removed at the end of the study. C) Tumor growth inhibition ratio. (IV: Intravenous; *: p < 0.05). Reproduced with permission.[ 122 ] Copyright 2018, American Chemical Society.