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. 2021 Nov 19;9(2):2102678. doi: 10.1002/advs.202102678

Figure 15.

Figure 15

Light‐responsive SrFe12O19/MBG/chitosan composite scaffold for simultaneous bone cancer therapy and regeneration in vivo. A) Micro‐CT images of defects after being implanted with different samples; blank control, mesoporous BG/chitosan (BCS), SrFe12O19–BG–chitosan (MBCS) at two different ratios of 1:3 (MBCS1:3) and 1:7 (MBCS1:7). B) Light images relating to the Van Giesons picrofuchsin‐stained sections of defects filled with the scaffolds up to 12 weeks. The new bone tissue and scaffolds can be seen in red and black, respectively. C) IR thermal images and D) temperature (°C) versus time (min) curves of the implanted MBCS1:3 scaffold into tumor‐bearing mice with and without laser irradiation. E) Fluorescence images of implanted MBCS1:3 scaffolds into tumor‐bearing mice with and without laser irradiation up to 12 days. F) The change in tumor size over time after being treated with the MBCS1:3 scaffolds, n = 5. Reproduced with permission.[ 172 ] Copyright 2018, Elsevier.