Table 3.
Light-evoked EPSCs | CON L5/6 | GE L5/6 | Neonatal CON L2/3 | GE L2/3 | F values | CON L5/6 | GE L5/6 | Prejuvenile CON L2/3 | GE L2/3 | F values | |
---|---|---|---|---|---|---|---|---|---|---|---|
Response % | 24/29 (82.76%) |
10/24 (41.67%) |
21/26 (80.76%) |
8/18 (44.44%) |
23/34 (67.65%) |
15/32 (46.88%) |
12/21 (57.14%) |
6/16 (37.5%) |
|||
Amplitude (pA) | 63.6 ± 12.12 **p = 0.001 |
9.72 ± 2.41 | 47.9 ± 12.00 | 40.97 ± 13.6 |
F(3,59) = 14.02 p = 0.0029 |
70.1 ± 13.74 *p = 0.0354 |
19.7 ± 4.39 | 43.0 ± 14.32 | 26.2 ± 15.96 |
F(3,52) = 9.877 p = 0.0196 |
|
CV | 0.236 ± 0.032 *p = 0.016 |
0.421 ± 0.052 | 0.390 ± 0.04 | 0.416 ± 0.066 |
F(3,59) = 5.35 p = 0.0026 |
0.34 ± 0.041 **p = 0.0005 |
0.60 ± 0.037 | 0.45 ± 0.063 | 0.40 ± 0.049 |
F(3,52) = 6.045 p = 0.0012 |
|
Onset delay (ms) |
5.15 ± 0.476 **p = 0.006 |
7.99 ± 0.762 | 6.29 ± 0.382 | 7.55 ± 1.128 |
F(3,59) = 5.00 p = 0.0037 |
4.41 ± 0.508 | 3.75 ± 0.506 ##p = 0.0044 |
4.89 ± 0.378 | 5.15 ± 0.861 |
F(3,52) = 5.967 p = 0.0014 |
|
Tau rise (ms) | 3.07 ± 0.044 *p = 0.022 |
3.60 ± 0.301 | 3.18 ± 0.093 | 3.06 ± 0.171 |
F(3,59) = 3.20 p = 0.030 |
3.63 ± 0.212 | 3.20 ± 0.158 | 3.31 ± 0.183 | 3.11 ± 0.159 |
F(3,52) = 1.358 p = 0.2651 |
|
PPR | 125 ms | 0.70 ± 0.056 | 0.48 ± 0.15 | 0.64 ± 0.09 | 0.63 ± 0.13 |
F(3,59) = 2.28 p = 0.5156 |
1.23 ± 0.09 *p = 0.037 |
0.94 ± 0.13 | 0.96 ± 0.12 *p = 0.0086 |
0.51 ± 0.12 |
F(3,52) = 17.11 p = 6.70E-04 |
250 ms | 0.72 ± 0.06 | 0.54 ± 0.08 | 0.69 ± 0.06 | 0.68 ± 0.15 |
F(3,59) = 3.95 p = 0.2672 |
1.35 ± 0.08 | 1.19 ± 0.14 | 1.07 ± 0.15 | 0.87 ± 0.14 |
F(3,52) = 8.88 p = 0.0310 |
|
500 ms | 0.66 ± 0.056 **p = 0.0061 |
0.27 ± 0.104 | 0.70 ± 0.069 | 0.62 ± 0.079 |
F(3,59) = 11.09 p = 0.0074 |
1.28 ± 0.111 | 1.23 ± 0.108 | 0.98 ± 0.105 | 1.03 ± 0.174 |
F(3,52) = 5.505 p = 0.1384 |
Data are shown as mean ± SEM. Significance was assessed using one-way ANOVA test followed by Bonferroni-corrected post hoc test. The listed p values (*p < 0.05, **p < 0.01) correspond to comparisons CON L5/6 versus GE L5/6 and CON L2/3 versus GE L2/3, whereas p values (##p < 0.01) correspond to comparisons CON L5/6 versus CON L2/3, GE L5/6 versus GE L2/3.