Spatiotemporal analysis of TEPs. TEPs (rectified) from left M1hand for the three sessions (Wristl-M1, noWristl-M1, and Wristr-M1) in the three blocks: pre-IVR, IVR, and post-IVR. (Panel A) Topography of voltage distribution represent TEPs from 40 to 230 ms for all the conditions and in the three blocks. (Panel B) Significant electrodes (p < 0.05) from the cluster-based comparison between pre-IVR and IVR block within the Wristl-M1 session are represented by gray and white circles; significant differences (p < 0.05) between the two IVR blocks of the Wristl-M1 and the noWristl-M1 conditions are represented by only gray circles. IVR, immersive virtual reality; TMS, transcranial magnetic stimulation; TEP, TMS-evoked potential; M1, primary motor cortex.