Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb;32(2):258–265. doi: 10.1101/gr.275636.121

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 Javidnia et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genome Research, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Figure 2. — MR analysis of association between expression of RP genes and longevity. (A) Levels of mRNA coding for RPs in the indicated tissues are shown. (B) MR analysis was performed using RP gene expression in indicated tissues as exposures and longevity (survival beyond the 90th or 99th percentile) as outcomes. The values of β are given per tissue and the significant associations indicated as those that pass the 10% FDR threshold (accounting for eight tissues and two outcomes, i.e., 16 tests). (C) MR scatter plot of association between RP expression in liver and longevity (90th percentile), showing results of two MR methods. Each black point denotes a cis-eQTL; green bars show SEM. Longevity β is the natural log of the odds ratio, where lower values indicate a lower chance of surviving beyond the 90th percentile. Expression β is reported as NESs, with larger values indicating higher expression, and refers to expression of multiple genes.