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In vitro cellular uptake and folic acid competition assay. MCF-7 cells incubation with free C6, C6-labeled MOF (MOF/C6), C6-labeled FA-MOF (FA-. MOF/C6), and C6-labeled MOF combined with 1 mM folic acid (FA MOF/C6) for 2 h. (A) Fluorescence images of cells were obtained by using a confocal laser scanning microscope; the scale bar was 20 µm. (B) Uptake efficiency on MCF-7 cells was obtained by flow cytometry and quantitative analysis. (C) **p < 0.01.
