Table 2.
Differences in response among the three groups.
| Baseline variable | C-SAP group (n = 33) | SAP group (n = 95) | P* value | SOX group (n = 72) | P # value | P & value |
|---|---|---|---|---|---|---|
| TRG | 0.034 | 0.029 | 0.543 | |||
| TRG1a | 8 (24.2) | 6 (6.3) | 4 (5.6) | |||
| TRG1b | 5 (15.2) | 19 (20.0) | 9 (12.5) | |||
| TRG2 | 6 (18.2) | 32 (33.7) | 24 (33.3) | |||
| TRG3 | 14 (42.4) | 38 (40.0) | 35 (48.6) | |||
| subgroup analysis | 0.157 | 0.019 | 0.207 | |||
| TRG1a-1b | 13 (39.4) | 25 (26.3) | 13 (18.1) | |||
| TRG2-3 | 20 (60.6) | 70 (73.7) | 59 (81.9) | |||
| ypTstage | 0.027 | 0.078 | 0.039 | |||
| T0 | 8 (24.2) | 6 (6.3) | 4 (5.6) | |||
| T1 | 2 (6.1) | 11 (11.6) | 4 (5.6) | |||
| T2 | 4 (12.1) | 12 (12.6) | 5 (6.9) | |||
| T3 | 13 (39.4) | 55 (57.9) | 37 (51.4) | |||
| T4a | 5 (15.2) | 11 (11.6) | 21 (29.2) | |||
| T4b | 1 (3.0) | 0 | 1 (1.4) | |||
| ypNstage | 0.055 | 0.056 | 0.563 | |||
| N0 | 22 (66.7) | 37 (38.9) | 26 (36.1) | |||
| N1 | 5 (15.2) | 21 (22.1) | 14 (19.4) | |||
| N2 | 2 (6.1) | 15 (15.8) | 12 (16.7) | |||
| N3a | 2 (6.1) | 17 (17.9) | 11 (15.3) | |||
| N3b | 2 (6.1) | 5 (5.3) | 9 (12.5) | |||
| ypTNMstage | 0.015 | 0.003 | 0.504 | |||
| pCR | 7 (21.2) | 5 (5.3) | 2 (2.8) | |||
| I | 6 (18.2) | 17 (17.9) | 9 (12.5) | |||
| II | 12 (36.4) | 35 (36.8) | 25 (34.7) | |||
| III | 8 (24.2) | 38 (40.0) | 36 (50.0) | |||
| ypTstage | 0.004 | 0.014 | 1 | |||
| T0 | 8 (24.22) | 6 (6.3) | 4 (5.6) | |||
| T1-T4b | 25 (75.8) | 89 (93.7) | 68 (94.4) | |||
| ypNstage | 0.006 | 0.004 | 0.708 | |||
| N0 | 22 (66.7) | 37 (38.9) | 26 (36.1) | |||
| N1-N3b | 11 (33.3) | 58 (61.1) | 46 (63.9) | |||
| ypTstage | 0.006 | 0.002 | 0.686 | |||
| pCR | 7 (21.2) | 5 (5.3) | 2 (2.8) | |||
| I-III | 26 (78.8) | 90 (94.7) | 70 (97.2) | |||
| Radiological response | 0.754 | 0.918 | 0.587 | |||
| PR | 30 (90.9) | 88 (92.6) | 65 (90.3) | |||
| SD | 3 (9.1) | 7 (7.4) | 7 (9.7) |
P*: C-SAP vs. SAP P#: C-SAP vs. SOX P&: SAP vs. SOX.