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Saxagliptin increased the expression of RUNX-2. Cells were stimulated with osteogenic differentiation induction medium (ODIM) in the presence or absence of Saxagliptin (1, 2 µM) for 14 days. (a). mRNA of RUNX-2; (b). Protein level of RUNX-2 (***, P < 0.005 vs. vehicle group; #, ##, P < 0.05, 0.01 vs. ODIM group, n = 5).
