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. 2022 Jan 8;13(1):1717–1735. doi: 10.1080/21655979.2021.2019873

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — The prognostic value of pyroptosis-related risk signature. (a) ROC curves of multiple different indexes for predicting patients’ survival outcomes. (b) Time-dependent ROC curves of PR model. (c) The univariate independent prognostic analysis. (d) The multivariate independent prognostic analysis. (e-n) Clinical subgroup prognostic analyses. (o) DCA results. ‘Model A’ represents the traditional prognostic model consisting of age, histological grade, and clinical stage. ‘Model B’ represents the traditional prognostic model consisting of age, histological grade, and TNM staging. ‘Improved A and B’ represent the improved model A and B with PR risk score added, respectively. (p) The nomogram predicting 1-, 3-, 5-year overall survival probability of PAAD patients. (o-s) Calibration curves of the nomogram. PR, pyroptosis-related; ROC, receiver operating characteristic curve; DCA, decision curve analysis; PAAD, pancreatic adenocarcinoma.