Figure 1 .

Study design and methods. (A) Hypothetical models of MCI progression. In pMCI, gradual cognitive decline continues until individuals meet the diagnostic criteria of AD. In sMCI, cognitive performance remains relatively stable over time. (B) Group allocation criteria. Cognitive evaluations at baseline and follow-up visits were used to classify subjects in the pMCI and sMCI groups. (C) Illustration of proposed deep learning model. Abbreviations: AD = Alzheimer’s disease, MCI = mild cognitive impairment, pMCI = progressive mild cognitive impairment, sMCI = stable mild cognitive impairment.