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. 2022 Jan 11;13(1):383–394. doi: 10.1080/21655979.2021.2005744

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — XYP induced up-regulation of Cx43/GR/BDNF could be blocked by GR antagonist, RU-486. A) Morphology changes in hippocampus and expression changes of GR and p-GR; B) Number of neurons from HE staining; C) Number of neurons from Nissl staining; D) Concentration of serum CORT; E) Effect of GR blocking on the expression of GR, p-GR, BDNF, Cx43, and c-Src; F) Quantification of western blots; G) Effect of GR blocking on GR and BDNF at mRNA level. * p ≤ 0.05 vs SD_XYP group; ** p ≤ 0.01 vs SD_XYP group.