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. 2022 Jan 11;13(1):1359–1376. doi: 10.1080/21655979.2021.2017588

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — lncRNA PURPL influenced GC progression via miR-137/ZBTB7A axis regulation miR-137 mimics (miR-137) or si-ZBTB7A was transfected into AGS cells with PURPL overexpression. A-C. RT-PCR confirmed the profiles of PURPL, miR-137, and ZBTB7A in AGS cells. D. Colony formation assay examined proliferation. E. Transwell monitored cell migration and invasion. F. Flow cytometry determined the apoptosis rate of AGS cells. G. The profiles of apoptosis-concerned proteins Bax, Bcl2, and Caspase3 were figured out through Western blot. ** P < 0.01, ***P < 0.001 (vs. the vec group), ##P < 0.01, ###P < 0.001 (vs. the PURPL group). N = 3.