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Down-regulation of the ZBTB7A/PI3K/AKT/NF-κB pathway mitigated PURPL’s level. si-ZBTB7A was transfected into AGS cells. A-B. RT-PCR examined PURPL and miR-137. C-F. LY294002 (10 μM) and JSH-23 (30 μM) were given to AGS cells for PI3K or NF-κB inhibition. RT-PCR assessed PURPL and miR-137. ***P < 0.001. N = 3.
