Figure 5.
Silencing B7-H4 inhibits tumor growth in mice. 5χ106 SW620 cells stably expressing sh-B7-H4 or sh-NC were inoculated subcutaneously in nude mice. a. The tumor volume was measured every 3 days in each group. b. The xenograft tumor weight in each group was weighed at the end of the experiment. c, d The mRNA expression levels of B7-H4 (c), Vimentin, N-cadherin and E-cadherin (d) in the tumor samples were assessed by RT-qPCR. e. The Ki67 and B7-H4 expression levels in tumor sections were assessed by IHC staining. Scale bar: 100 μm *, P < 0.05, **, P < 0.01, and ***, P < 0.001. The error bars are defined as S.D