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. 2021 Dec 29;13(1):395–406. doi: 10.1080/21655979.2021.2005929

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — DDAH2 is involved in the inhibition of sh-KLF9 on the oxidative stress and inflammation of HG-induced HTR8/SVneo cells. The detection of (a) ROS, (b) NOS and (c) NO in HG-induced HTR8/SVneo cells co-transfected with sh-KLF9 and sh-DDAH2 detected by corresponding kits. The (d) inflammatory factors and (e) expression of inflammation-related markers detected respectively by ELISA and Western blot. ***p < 0.001 vs HG; ###p < 0.001 vs HG+sh-NC; +, ++, +++p < 0.05, 0.01, 0.001 vs HG+sh-KLF9+ sh-NC.