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. 2022 Jan 3;13(1):810–823. doi: 10.1080/21655979.2021.2012952

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — The function of circPTK2 knockdown on cell proliferation, migration, invasion and chemoresistance in CRC cells. HT-29 and LoVo cells were transfected with sh-NC, sh-circPTK2-1 or sh-circPTK2-2. (a) circPTK2 abundance was determined by qRT-PCR. (b and c) Cell proliferation was detected by CCK-8 assay. (d and e) Colony formation was analyzed by colony formation assay. (f-i) Cell migration and invasion were measured by transwell assay. (j-m) Cell viability was determined by CCK-8 assay. (n and o) β-catenin and cyclin D1 abundances were measured by WB analysis. ***P < 0.001.