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. 2022 Jan 31;13(1):469–480. doi: 10.1080/21655979.2021.2009414

Figure 5.

Figure 5.

Inhibiting miR-149-5p rescues down-regulated circ_0000654-induced anti-tumor effect on GC. A. Proliferation of BGC-823 cells co-transfected with si-circ_0000654 and miR-149-5p-inhibitor (CCK-8 assay); B. Apoptosis of BGC-823 cells co-transfected with si-circ_0000654 and miR-149-5p-inhibitor (flow cytometry); C. Migration of BGC-823 cells co-transfected with si-circ_0000654 and miR-149-5p-inhibitor (scratch test); D. Invasion of BGC-823 cells co-transfected with si-circ_0000654 and miR-149-5p-inhibitor (Transwell assay); E. INHBA expression in BGC-823 cells co-transfected with si-circ_0000654 and miR-149-5p-inhibitor (RT-qPCR and Western blot). The value was expressed as mean ± standard deviation. Experimental repetitions = 3. Data comparison used t test, * P < 0.05 vs. the si-circ_0000654 + NC inhibitor group.