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. 2022 Jan 4;13(1):1459–1475. doi: 10.1080/21655979.2021.2019871

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Preparation of PASP-PLGA microcapsules for sustained release of BMP-2. (a) Technical route to establish the PASP-PLGA microcapsules. (b) Encapsulation efficiency analysis invest with in 5, 10 and 20 mg BMP-2 for PASP-PLGA microcapsules. All tests were repeated three times in triplicate. (c) Sustained release of BMP-2 tests in vitro. All tests were repeated three times in triplicate. (d) The concentration of BMP-2 was detected in the rabbit models of tendon-bone repair after acute rotator cuff rupture at 4 weeks after treatment. *p < 0.05 vs. control group. The data were expressed as mean ± standard deviation.