Skip to main content
. 2022 Jan 5;13(1):774–788. doi: 10.1080/21655979.2021.2012919

Figure 5.

Figure 5.

Role of miR-188-3p on the therapeutic effect of germacrone on DN. (a) Blood samples were collected from WT, STZ-induced mice and blood glucose was determined using an Omron Glucometer, **P < 0.01. (b–f) Urine and blood samples of WT, STZ-induced mice, STZ+germacrone co-treated mice, STZ+germacrone+miR-188-3p agomir co-induced mice and STZ+germacrone+miR-188-3p agomir NC co-treated mice were collected, and 24 h proteinuria, BUN, and BUA were analyzed using a Fully automatic biochemical analyzer. Ucr and Scr were measured with the homologous ELISA kits, **P < 0.01. (g–h) Kidney paraffin sections obtained from the different groups underwent HE and PAS staining. Magnification: ×400. Scale bar: 100 μm.