Figure 3.

miR-373-3p hampered tumor growth and boosted apoptosis in vivo.

The Huh7 cell line was transfected along with Lv-miR-373-3p or Lv-miR-NC and then was transfused subcutaneously into the armpits of the nude mice. (a–c): Tumor formation assay in nude mice examined the tumor size and weight; (d): IHC measured tumor cell proliferation (labeled by KI-67). (e–f): Western blot confirmed the profiles of Bax, Bcl2, caspase 3, and EMT-concerned markers (E-cadherin, vimentin, Snail) in the tumors we evaluated. NsP > 0.05, **P < 0.01, ***P < 0.001 (vs. the NC group). N = 5.