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. 2021 Dec 29;13(1):800–809. doi: 10.1080/21655979.2021.2012950

Figure 8.

Figure 8.

Sitagliptin prevented hypoxia-induced activation of NF-κB. Cells were stimulated with Sitagliptin (100, 200 nM) for 2 hours, followed by exposure to hypoxia for 6 hours. (a). Nuclear levels of NF-κB p65; (b). Luciferase activity of NF-κB promoter (****, P < 0.0001 vs. vehicle group; #, ##, P < 0.05, 0.01 vs. Sitagliptin group, n = 6).