Fig. 1.

49 years old male patient underwent a CCTA (coronary CT angiography) for atipical chest pain. Images show mid- LAD soft, moderate plaque on multiplanar reconstruction (A, arrow) and cross-sectional view (B, arrow); this plaque does not present high risk features (positive remodeling, low attenuation, spotty calcification, napkin-ring sign). Histopathology on H&E is shown in C and D. C: atherosclerotic plaque with intraplaque hemorrhage (arrowhead) and neoangiogenesis with severe inflammation (arrow). D: Higher magnification of neoangigenesis inside the atherosclerotic plaque. The hemosiderin deposits, appearing as yellow–brown granules, are the sign of previous intraplaque hemorrhages.