Table 1.
Studies regarding coronary imaging in COVID-19 patients.
| Authors | Vascular segments | Number (patients) | Date published | Research | Main results |
|---|---|---|---|---|---|
| Dillinger et al. (28) | Coronary arteries | 209 | 2020 | Evaluation of coronary artery calcification (CAC) using CT within 24 h of admission in patients with no history of CVD | CAC is significantly associated with a primary outcome (noninvasive or invasive mechanical ventilation, ECMO, death within 30 days after admission) |
| Nai Fovino (29) | Coronary arteries | 53 | 2020 | CAC evaluation in hospitalized COVID- 19 patients without known CAD | CAC > 400 is significantly associated with in-hospital mortality and ICU admission |
| Scoccia et al. (30) | Coronary arteries | 1625 | 2021 | Prognostic impact of clinical and subclinical CAD, as assessed by CAC score | Presence and extent of CAD are associated with in-hospital mortality and MI/CVAamong hospitalized patients and they appear to be a better prognostic gauge as compared to a clinical CV risk assessment |
| Grodecki et al. (51) | Epicardial adipose tissue (EAT) | 109 | 2021 | Association of EAT quantified on CT with the extent of pneumonia and adverse outcomes in patients with COVID- 19. | EAT is independently associated with extent of pneumonia and adverse outcomes in patients with COVID-19 |
| Hui et al. (52) | EAT | 41 | 2020 | Correlation between clinical characteristics and cardiac injury of COVID-2019 pneumonia |
Critical and severe COVID-19 patients show lower EAT density values, indicatingcardiac inflammation |
| Kotanidis et al. (54) | Perivascular adipose tissue | 435 | 2021 | Radiotranscriptomic signature (C19-RS), quantifying cytokine- driven vascular inflammation in patients with acute COVID-19, as a risk stratification tool | COVID-19 patients have high C19-RS values; B.1.1.7 variant has higher C19-RS values. C19-RS has prognostic value for in- hospital mortality. |
| Kotanidis et al. (55) | Perivascular adipose tissue (PVAT) | 201 | 2020 | CTA-based radiotranscriptomic phenotyping of PVAT may quantify COVID- 19-induced vascular inflammation, predicting clinical outcomes |
C19-RS was significantly associated with in-hospital death and a composite endpointofin- hospital deathandICU admission |
| Stefanini et al (61) |
Coronary arteries |
28 | 2020 | Incidence, clinical presentation, angiographic findings, and clinical outcomes evaluation of STEMI in COVID-19 patients |
STEMI may represent the first clinical manifestation ofCOVID-19,butin approximately40%of cases a culprit lesion is not identifiable by coronary angiography. |