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. 2022 Jan 10;13(1):1530–1540. doi: 10.1080/21655979.2021.2021701

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — DHA inhibits migration and induces cell differentiation in IL-17A-stimulated HaCaT cells by targeting FGFR1. (a) Cell migration was detected by using wound healing; (b) Cell migration-related protein expressions were analyzed by Western blotting, including MMP2 and MMP9; (c) Cell differentiation-related protein expressions were analyzed by Western blotting, including keratin1, keratin 10, involucrin and filaggrin. ***P < 0.001 vs. control. ###P < 0.001 vs. IL-17A. ^ΔP<0.05, ^ΔΔP<0.01 and ^ΔΔΔP<0.001 vs. IL-17A+DHA. DHA, dihydroartemisinin.