Table 1.
Participant Demographics at Baseline
| Characteristic | Total (N=441) | MCI (N=313) | AD (N=128) | p-value |
|---|---|---|---|---|
| Age (Years) | 72.5 (7.7) | 71.7 (7.3) | 74.4 (8.4) | 0.001 |
| Female (n, %) | 191 (43.3) | 140 (44.7) | 51 (39.8) | 0.347 |
| Education (Years) | 16.2 (2.6) | 16.4 (2.6) | 15.8 (2.6) | 0.021 |
| Tau/Aβ42 ratio* | 0.73 (0.55) | 0.60 (0.47) | 1.05 (0.60) | <0.001 |
| MEM Cognitive Composite | −0.073 (0.82) | 0.25 (0.70) | −0.88 (0.49) | <0.001 |
| EF Cognitive Composite | −0.028 (1.07) | 0.32 (0.92) | −0.87 (0.96) | <0.001 |
| MEM Pathology Composite | 0 (0.34) | −0.12(0.30) | 0.27(0.27) | <0.001 |
| EF Pathology Composite | 0 (0.45) | −0.14(0.40) | 0.34(0.36) | <0.001 |
Demographic, pathology, and performance information is displayed for all participants. Reported values are mean with standard deviation, beside gender. Those with AD were significantly older, had greater AD pathology burden, were less educated, and performed worse on neurocognitive testing than those with MCI.
*
A total of 15 participants were missing data on this component of the pathology composite.