Table 1.
Clinical and Histopathological Characteristics (n=859) | Result |
---|---|
eGFR, mean (SD), ml/min per 1.73 m2 | 65 (26.7) |
Age, mean (SD), yr | 61 (13) |
DM, n (%) | 304 (35.4) |
HTN, n (%) | 595 (69) |
Sex, M, n (%) | 548 (63.8) |
Race, Black, n (%) | 176 (20.4) |
BMI, median (IQR), kg/m2 | 29.4 (25.7–34.2) |
Systolic BP, mean (SD), mm Hg | 136 (20) |
Diastolic BP, mean (SD), mm Hg | 77 (12) |
Serum albumin, median (IQR), g/dl | 4.05 (3.7–4.4) |
Dipstick proteinuria (%) | |
Negative | 54.9 |
Trace | 9.2 |
30 mg/dl | 14.9 |
100 mg/dl | 12.5 |
300 mg/dl | 1.3 |
>1000 mg/dl | 7.6 |
Tubulointerstitial | |
Acute tubular injury, median (IQR) (%) | 0 (0–2) |
TA, median (IQR) (%) | 5 (2–10) |
Tubular reabsorption 0–3 (%) | |
0 | 81.4 |
1 | 16.1 |
2 | 2.1 |
3 | 0.5 |
Interstitial fibrosis, median (IQR) (%) | 5 (2–15) |
Interstitial eosinophils 0–3 (%) | |
0 | 78.8 |
1 | 19.6 |
2 | 1.4 |
3 | 0.2 |
Interstitial lymphocytic infiltrates 0–3 (%) | |
0 | 25.7 |
1 | 48.3 |
2 | 19.7 |
3 | 6.3 |
Interstitial plasmocytic infiltrates 0–3 (%) | |
0 | 65.4 |
1 | 28.3 |
2 | 5.4 |
3 | 0.9 |
Glomerular | |
Segmental sclerosis, median (IQR) (range) (%) | 0 (0) (0–29) |
GS, median (IQR) (%) | 6.7 (2.7–16.1) |
Wall thickening 0–3 (%) | |
0 | 88.9 |
1 | 7.2 |
2 | 2.9 |
3 | 1 |
Hypoperfused 0–3 (%) | |
0 | 33.7 |
1 | 53.7 |
2 | 9.8 |
3 | 2.8 |
Mesangial matrix 0–3 (%) | |
0 | 78.2 |
1 | 13.2 |
2 | 4.4 |
3 | 4.2 |
Mesangial cellularity 0–3 (%) | |
0 | 83.1 |
1 | 9.4 |
2 | 4.3 |
3 | 3.1 |
KW nodules present (%) | 3.5 |
Pericapsular fibrosis 0–3 (%) | |
0 | 43.7 |
1 | 41.7 |
2 | 14.5 |
3 | 0.1 |
Vascular | |
Arteriolar hyalinosis 0–3 (%) | |
0 | 67.3 |
1 | 23.6 |
2 | 6.3 |
3 | 2.8 |
Intimal fibrosis 0–3 (%) | |
0 | 13.7 |
1 | 41.2 |
2 | 32.4 |
3 | 12.7 |
IQR, interquartile range; M, male.