Table 3.

Clinical and histopathological variables associated with kidney function decline: Clinical and histopathologic characteristics of longitudinal cohort

Clinical and Pathologic Characteristics of Follow-up Data (n=280)	Result
eGFR, mean (SD), ml/min per 1.73 m2	65.7 (24.2)
Follow up eGFR, mean (SD), ml/min per 1.73 m2	53.9 (24.8)
Age, mean (SD), yr	62.8 (12)
DM, n (%)	107 (38.2)
HTN n (%)	206 (73.6)
Sex, M, n (%)	168 (60)
Race, Black, n (%)	56 (20)
BMI, mean (SD), kg/m2	31.5 (7.5)
Systolic BP, mean (SD), mm Hg	137 (22)
Diastolic BP, mean (SD), mm Hg	77 (12)
Follow up eGFR slope, median (IQR) ml/min per 1.73 m2/yr	−4.8 (−12.2 to −1.3)
Percent eGFR slope change/yr, median (IQR)	−6.7 (−17.4 to −2.0)
Partial/total nephrectomy (%)	29.2/70.8
Tumor size, mean (SD) cm	6.2 (3.5)
Tubulointerstitial
Acute tubular injury, median (IQR) (%)	0 (0–2)
TA, median (IQR) (%)	5 (2–10)
Tubular reabsorption 0–3 (%)
0	81.1
1	15.7
2	2.5
3	0.7
Interstitial fibrosis, median (IQR) (%)	5 (2–10)
Interstitial eosinophils 0–3 (%)	81.1/17.9/1.1
0	81.1
1	17.9
2	1.1
3	0
Interstitial lymphocytic infiltrates 0–3 (%)
0	27.1
1	53.2
2	16.1
3	3.6
Interstitial plasma cell infiltrates 0–3 (%)
0	69.6
1	26.1
2	3.9
3	0.4
Glomerular
Segmental sclerosis, median (IQR) (range) (%)	0 (0)
GS, median (IQR) (%)	5.8 (2.8–12.7)
Wall thickening 0–3 (%)
0	91.4
1	5
2	3.2
3	0.4
Hypoperfused 0–3 (%)
0	34.3
1	56.4
2	8.6
3	0.7
Mesangial matrix 0–3 (%)
0	77.7
1	13.3
2	4.5
3	4.4
Mesangial cellularity 0–3 (%)
0	82.5
1	11.8
2	3.2
3	2.5
KW nodules present (%)	2.9
Pericapsular fibrosis 0–3 (%)
0	42.1
1	46.8
2	11.1
3	0
Vascular
Arteriolar hyalinosis 0–3 (%)
0	69.6
1	24.6
2	3.9
3	1.8
Intimal fibrosis 0–3 (%)
0	12.5
1	45.7
2	35.7
3	6.1

IQR, interquartile range; M, male.