Table 5.
Clinical and histopathological variables associated with kidney function decline: Variables (fixed effects) associated with eGFR decline in linear mixed model in subjects with eGFR≥60 at time of nephrectomy
| Longitudinal eGFR, if Baseline eGFR>60 (n=99) | Coefficient | SE | z | P>|z| | 95% Confidence Interval | |
|---|---|---|---|---|---|---|
| Age (per 1 year older) | −0.25 | 0.09 | −2.88 | <0.01 | −0.41 | −0.08 |
| eGFR baseline (per 1 ml/min per 1.73 m2) | 0.75 | 0.06 | 12.45 | <0.001 | 0.63 | 0.87 |
| GS (per 1% difference) | −0.28 | 0.09 | −2.94 | <0.01 | −0.46 | -0.09 |
| Radical nephrectomy (yes/no) | −6.19 | 1.89 | −3.27 | <0.01 | −9.90 | −2.48 |
| Tumor size (per 1 cm) | 0.38 | 0.26 | 1.47 | 0.14 | −0.13 | 0.89 |
| Sex, F (yes/no) | −2.25 | 1.84 | −1.22 | 0.22 | −5.85 | 1.35 |
| Race, Black (yes/no) | −2.88 | 2.70 | −1.07 | 0.29 | −8.17 | 2.40 |
| BMI (per 1 kg/m2) | 0.05 | 0.11 | 0.43 | 0.67 | −0.17 | 0.26 |
| Diabetes (yes/no) | 0.65 | 1.75 | 0.37 | 0.71 | −2.78 | 4.08 |
| HTN (yes/no) | −0.40 | 1.89 | −0.21 | 0.83 | −4.10 | 3.30 |
| Length of follow up time (per 1 year difference) | −0.04 | 0.16 | −0.25 | 0.80 | −0.36 | 0.28 |
F, female.