Table 3.
Comparison of podocyte mean nuclear caliper diameters and CF values in PAS and IF/IHC images
| Species | Podocyte Nuclei Marker | Disease State | On the basis of PAS Images | On the basis of IF/IHC Images | Average Absolute Error in CF (|CFPAS-CFIF/IHC|) | ||
|---|---|---|---|---|---|---|---|
| DPAS (µm) | CF PAS | DIF/IHC (µm) | CF IF/IHC | ||||
| Mouse | p57 | Control | 6.81±0.24 | 0.31±0.01 | 6.20±0.26 | 0.32±0.01 | 0.01 |
| Mouse | p57 | NTN | 6.73±0.48 | 0.31±0.01 | 7.05±0.27 | 0.30±0.01 | 0.01 |
| Rat | p57 | Control | 7.19±0.31 | 0.22±0.01 | 7.79±0.87 | 0.21±0.02 | 0.01 |
| Rat | p57 | PAN | 6.92±0.22 | 0.22±0.01 | 8.10±0.69 | 0.20±0.01 | 0.02 |
| Human | p57 | Biopsy | 6.62±0.28 | 0.23±0.01 | 7.85±0.89 | 0.21±0.02 | 0.02 |
| Human | p57 | Autopsy | 7.98±0.84 | 0.33±0.02 | 8.33±1.17 | 0.33±0.03 | 0.00 |
The absolute error in CF values on the basis of true D extracted from PAS and IF/IHC images. The results indicate that the calculated CF values remain relatively unchanged between the IF/IHC and PAS images. NTN, nephrotoxic nephritis.