Table 1.
Baseline characteristics
| Characteristics | All Donors | BMI <30 kg/m2 | BMI 30–34.9 kg/m2 | BMI ≥35 kg/m2 | P Value |
|---|---|---|---|---|---|
| (n=8583) | (n=6822) | (n=1338) | (n=423) | ||
| Age (years) | 39 (31, 48) | 39 (30, 48) | 41 (33, 49) | 38 (32, 46) | <0.001 |
| Male | 3756 (43.8) | 2988 (43.8) | 626 (46.8) | 142 (33.6) | <0.001 |
| Race/ethnicity | <0.001 | ||||
| Non-Hispanic White | 7300 (85.1) | 5855 (85.8) | 1117 (83.5) | 328 (77.5) | |
| Non-Hispanic Black | 784 (9.1) | 564 (8.3) | 153 (11.4) | 67 (15.8) | |
| Hispanic | 162 (1.9) | 119 (1.7) | 33 (2.5) | 10 (2.4) | |
| Non-Hispanic Asian | 78 (0.9) | 72 (1.1) | 4 (0.3) | 2 (0.5) | |
| Other | 114 (1.3) | 87 (1.3) | 19 (1.4) | 8 (1.9) | |
| Unknown | 145 (1.7) | 125 (1.8) | 12 (0.9) | 8 (1.9) | |
| Related to recipient | 6868 (80.2) | 5511 (81.0) | 1018 (76.4) | 339 (80.3) | <0.001 |
| 1st degree relative with hypertension | 3230 (41.2) | 2491 (40.0) | 558 (45.3) | 181 (46.8) | <0.001 |
| 1st degree relative with diabetes | 3132 (39.1) | 2478 (39.0) | 465 (37.2) | 189 (47.8) | <0.001 |
| 1st degree relative with kidney disease | 5879 (71.5) | 4749 (72.6) | 848 (66.3) | 282 (69.8) | <0.001 |
| 1st degree relative with heart disease | 2318 (29.6) | 1783 (28.7) | 396 (32.2) | 139 (36.1) | <0.001 |
| BMI (kg/m2) | 25.8 (22.9, 29.2) | 24.6 (22.3, 27.0) | 31.8 (30.8, 33.0) | 37.0 (35.8, 39.0) | <0.001 |
| Systolic BP (mmHg) | 121 (113, 130) | 120 (112, 129) | 125 (118, 133) | 127 (120, 135) | <0.001 |
| Diastolic BP (mmHg) | 74 (68, 80) | 73 (68, 79) | 75 (70, 81) | 76 (70, 81) | <0.001 |
| Smoking | 4063 (48.5) | 3307 (50) | 591 (45.3) | 165 (39.6) | <0.001 |
| Total cholesterol (mg/dl) | 193 (169, 218) | 191 (167, 216) | 200 (178, 225) | 196 (173, 221) | <0.001 |
| LDL (mg/dl) | 115 (94, 137) | 113 (92, 136) | 121 (100, 142) | 116 (97, 140) | <0.001 |
| HDL (mg/dl) | 51 (42, 62) | 52 (43, 64) | 46 (39, 56) | 45 (38, 54) | <0.001 |
| Triglyceride (mg/dl) | 104 (75, 148) | 97 (71, 138) | 128 (90, 191) | 141 (106, 204) | <0.001 |
| Fasting glucose (mg/dl) | 92 (85, 99) | 91 (85, 99) | 95 (89, 102) | 95 (88, 103) | <0.001 |
| Serum creatinine (mg/dl) | 0.9 (0.8, 1.1) | 0.9 (0.8, 1.1) | 1 (0.8, 1.1) | 0.9 (0.8, 1.1) | <0.001 |
| eGFR (ml/min per 1.73m2) | 88 (76, 101) | 89 (77, 102) | 86 (75, 99) | 88 (74, 103) | <0.001 |
| Donation to end of follow-up (year) | 14 (8, 25) | 15 (9, 27) | 11 (7, 18) | 11 (8, 17) | <0.001 |
Values are in frequency and % for categorical variables and median (IQR) for continuous variables.