Table 6.
Baseline characteristics of donors who developed ESKD
| Characteristics | All donors with ESKD (n=43) | BMI <30 kg/m2 (n=31) | BMI 30.0-34.9 kg/m2 (n=8) | BMI ≥35 kg/m2 (n=4) | P Value |
|---|---|---|---|---|---|
| Age (yrs) | 41 (30, 50) | 41 (27, 43) | 47 (40, 52) | 47 (34, 51) | 0.22 |
| Male | 22 (51.2) | 16 (51.6) | 5 (62.5) | 1 (25.0) | 0.55 |
| Race/ethnicity | 1.00 | ||||
| Non-Hispanic White | 34 (79.1) | 23 (74.2) | 7 (87.5) | 4 (100.0) | |
| Non-Hispanic Black | 5 (11.6) | 4 (12.9) | 1 (12.5) | 0 (0.0) | |
| Hispanic | 1 (2.3) | 1 (3.2) | 0 (0.0) | 0 (0.0) | |
| Non-Hispanic Asian | 1 (2.3) | 1 (3.2) | 0 (0.0) | 0 (0.0) | |
| Other | 2 (4.7) | 2 (6.5) | 0 (0.0) | 0 (0.0) | |
| Related to recipient | 40 (93.0) | 30 (96.8) | 6 (75.0) | 4 (100.0) | 0.10 |
| 1st degree relative with hypertension | 22 (56.4) | 16 (57.1) | 4 (57.1) | 2 (50.0) | 1.00 |
| 1st degree relative with diabetes | 14 (35.0) | 10 (35.7) | 2 (25.0) | 2 (50.0) | 0.67 |
| 1st degree relative with kidney disease | 33 (76.7) | 26 (83.9) | 5 (62.5) | 2 (50.0) | 0.18 |
| 1st degree relative with heart disease | 14 (36.8) | 12 (44.4) | 1 (14.3) | 1 (25.0) | 0.43 |
| BMI (kg/m2) | 27.8 (24.1, 30.7) | 25 (23.6, 28) | 31.5 (30.9, 32.8) | 36.3 (35.8, 39.0) | <0.001 |
| Systolic BP (mmHg) | 123 (114, 130) | 120 (113, 129) | 124 (119, 130) | 130 (126, 133) | 0.14 |
| Diastolic BP (mmHg) | 78 (71, 82) | 77 (71, 80) | 78 (70, 83) | 84 (81, 85) | 0.09 |
| Smoking | 25 (64.1) | 18 (62.1) | 4 (66.7) | 3 (75) | 1.00 |
| Total cholesterol (mg/dl) | 205 (175, 215) | 201 (174, 208) | 232 (211, 252) | 171 (171, 171) | 0.06 |
| LDL (mg/dl) | 91 (47, 161) | 69 (47, 91) | 161 (161, 161) | – | 0.22 |
| HDL (mg/dl) | 47 (38, 56) | 44 (35, 53) | 50 (41, 59) | – | 0.44 |
| Triglyceride (mg/dl) | 140 (90, 195) | 172 (105, 281) | 137 (101, 165) | 85 (56, 114) | 0.27 |
| Fasting glucose (mg/dl) | 92 (84, 104) | 92 (82, 103) | 94 (84, 113) | 90 (68, 96) | 0.51 |
| Serum creatinine (mg/dl) | 1.0 (0.8, 1.1) | 1.0 (0.8, 1.1) | 1.1 (1.0, 1.2) | 1.0 (0.8, 1.1) | 0.22 |
| eGFR (ml/min per 1.73m2) | 83 (76, 104) | 92 (79, 107) | 82 (71, 85) | 73 (67, 99) | 0.14 |
| Donation to end of follow-up (year) | 34 (21, 39) | 36 (20, 39) | 26 (20, 30) | 30 (26, 37) | 0.11 |
Values are in frequency and % for categorical variables and median (IQR) for continuous variables.