Table 3.

Biomarker characteristics in cohort 2 (n=84) compared with adjudication committee diagnosis of RV flare or non-RV flare

Diagnostic Tool	% (95% CI)
	Sensitivity	Specificity	PPV	NPV	FP/FN	AUC (95% CI)
usCD163 >250 ng/mmol	96.8 (83.3 to 99.9)	86.8 (74.7 to 94.5)	81.1 (68.2 to 89.6)	97.9 (82.1 to 95.8)	7/1	0.950 (0.90 to 0.99)
Physician impression of high probability	90.3% (74.2 to 97.9)	79.2 (65.9 to 89.2)	71.8 (56.3 to 92.3)	93.3 (81.2 to 96.7)	11/3	0.848 (0.771 to 0.924)

PPV, positive predictive value; NPV, negative predictive value; FP, false positive; FN, false negative.