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. 2022 Feb 1;36(2):397–421. doi: 10.1016/j.idc.2022.01.006

Table 2.

Studies of monoclonal antibodies in solid organ transplant patients

Study Population Monoclonal Antibody Outcomes
Yetmar et al.69 73 patients with lung, liver, kidney, and heart transplant Bamlanivimab
  • 1.

    12.3% of patients required hospitalization for median of 4 d.

  • 2.

    No deaths

Klein et al.70 20 of 95 kidney transplant patients Balmanivimab
  • 1.

    mAb administration led to 15% vs 76% emergency department/hospital visits (P < .001).

Del Bello et al.71 16/48 patients with kidney, kidney-liver, kidney-heart 5 bamlanivimab
9 bamlanivimab + etesevimab
2 casirivimab + imdevimab
  • 1.

    0 vs 46% patients developed severe respiratory failure in the non-mAb group (P = .007).

Jenks et al.72 175/617 high-risk patients 83% received bamlanivimab + etesevimab
16% bamlanivimab
1.7% vs 24% hospitalizations and 0 vs 2.7% deaths in mAb vs non-mAb groups, respectively

aBamlanivimab or bamlanivimab + etesevimab research are presented for context, but these drugs no longer may be appropriate, depending on circulating variants of concern.