Table 2.
miRNA selection and expression verification
| miRNA ID | HCT116-TPM | IL_18-TPM | log2 Ratio (IL_18/HCT166) | Up-Down-Regulation (IL_18/HCT166) | P-value | FDR | Target Genes |
|---|---|---|---|---|---|---|---|
| miR-615-5p | 130.3934 | 37.5106 | −1.7975 | Down | 0 | 2.29E-104 | IGF2, RAB24 |
| miR-7-1-3p | 1601.105 | 927.1425 | −0.7882 | Down | 0 | 0 | EGFR, IGF1R, RAF1, KCNJ2 |
| let-7c-5p | 343.9652 | 220.3056 | −0.64276 | Down | 0 | 3.95E-49 | CDC25A, TGFBR1, MYC |
| miR-574-3p | 89.27742 | 57.75968 | −0.62823 | Down | 0 | 1.30E-12 | EGFR, SMAD4, TGFB1 |
| miR-510-3p | 80.33917 | 23.23665 | −1.7897 | Down | 0 | 5.64E-64 | IL-17A, IL-17, ZNF790 |