Figure 3.

IL-23 significantly increases pSTAT3 expression in pSS patient-derived PBMCs, depending on the expression of IL-23 R: (a) MFI of pSTAT3 (Y705) in CD4⁺ and CD8⁺ T cells before and after IL-23 stimulation of PBMCs by flow cytometry. (b) FC of the MFI of pSTAT3 (Y705) before and after IL-23 stimulation. (c) IL-23 R protein expression in PBMCs by WB. (d, e) MFI of mIL-23 R in CD4⁺ and CD8⁺ T cells by flow cytometry. ns: not significant, * p ≤ 0.05, ** p ≤ 0.05, *** p ≤ 0.001 by ANOVA or Student’s t-test