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. 2021 Jan 11;12(1):369–381. doi: 10.1080/21655979.2020.1868742

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — IRAK1 regulates the malignant phenotypes of PDAC cells

A. siRNA targeting IRAK1 and negative control siRNA were respectively transfected into BxPC-3 and Colo357 cells, and the expression of IRAK1 in the two cell lines was detected by Western blot.B. CCK-8 method was used to detect the proliferation of BxPC-3 and Colo357 cells after knocking down IRAK1.C-D. Brdu assay was used to detect the proliferation of BxPC-3 and Colo357 cells after knocking down IRAK1. Scale bar = 200 µm.E-F. Transwell assay was used to detect migration and invasion of BxPC-3 and Colo357 cells after knocking down IRAK1. Scale bar = 200 µm.** P < 0.01 and *** P < 0.001.