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. 2021 Feb 22;12(1):708–719. doi: 10.1080/21655979.2021.1883279

Figure 4.

Figure 4.

PDE4B acts as a target of miR-124-3p

A. Bioinformatics was used to predict the binding sites between miR-124-3p and 3ʹ-UTR of PDE4B. B. Dual-luciferase reporter assay verified the targeted binding relationship between miR-124-3p and PDE4B. C-D. After the expression of NEAT1 and miR-124-3p were selectively regulated, qRT-PCR and western blot were used to analyze the expression of PDE4B mRNA and protein. All experiments were performed in triplicate. **P < 0.01, and ***P < 0.001.