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. 2021 Jun 2;12(1):1874–1889. doi: 10.1080/21655979.2021.1924544

Figure 1.

Figure 1.

FTO and STAT3 expression in doxorubicin-resistant BC cells. a, b The sensitivity of doxorubicin-resistant MCF-7 and MDA-MB-231 cells and their parental cells to doxorubicin. c The IC50 value of doxorubicin against doxorubicin-resistant MCF-7 and MDA-MB-231 cells and their parental cells. d, e The mRNA level of FTO and STAT3 in doxorubicin-resistant BC cells and their parental cells. f, g The protein expression of FTO, p-STAT3 and STAT3 in doxorubicin-resistant BC cells and their parental cells. **p < 0.01. MCF-7-DoxR, doxorubicin-resistant MCF-7; MDA-MB-231-DoxR, doxorubicin-resistant MDA-MB-231; IC50, half-maximal (50%) inhibitory concentration; p-STAT3, phosopho-STAT3Tyr705