Table 3.

Top 10 significant Kyoto Encyclopedia of Genes and Genome pathways of SYNJ2 and differentially coexpressed genes

Term	Count	Genes	Fold Enrichment	P-value	FDR
Metabolic pathways	59	HEXA, HEXB, IL4I1, GLDC, ASPA, TDO2, SCLY, MAT1A, CYP7A1, HDC, GSTZ1, SYNJ2, HPD, AADAT, HMGCLL1, CYP1A1, ACADS, HAL, ALDH3B2, CYP26A1, ACADL, TAT, GLUL, CTH, SDS, AKR1B10, HAO2, UROC1, AKR1D1, OAT, PRODH, BCAT1, FUT5, AASS, KMO, GLS2, ARG1, MTHFS, CSAD, ADH4, HK3, ALDH4A1, ENO3, CDA, FUT2, INPP5B, BCKDHA, NOS1, AMACR, FTCD, ACACB, DBH, PCK1, CEL, AMDHD1, GCK, AGXT2, CYP4F2, CBS	4.8963	6.60E-35	7.41E-32
Biosynthesis of antibiotics	17	AADAT, BCAT1, BCKDHA, AASS, TAT, PCK1, GLDC, ARG1, CTH, GCK, SDS, HK3, HAO2, ENO3, OAT, CBS, PRODH	8.1120	1.05E-10	1.19E-07
Histidine metabolism	7	AMDHD1, ASPA, HDC, FTCD, HAL, ALDH3B2, UROC1	32.1878	4.49E-08	5.04E-05
Biosynthesis of amino acids	9	BCAT1, ARG1, GLUL, CTH, MAT1A, SDS, ENO3, TAT, CBS	12.6452	3.86E-07	4.34E-04
Tyrosine metabolism	7	ADH4, GSTZ1, ALDH3B2, IL4I1, DBH, TAT, HPD	20.2324	8.84E-07	9.94E-04
Primary bile acid biosynthesis	5	CYP39A1, CYP46A1, CYP7A1, AMACR, AKR1D1	29.7535	1.78E-05	0.0200
Alanine, aspartate and glutamate metabolism	6	GLS2, GLUL, ASPA, ALDH4A1, IL4I1, AGXT2	17.3420	1.95E-05	0.0219
Cysteine and methionine metabolism	6	CTH, MAT1A, SDS, IL4I1, TAT, CBS	15.9729	2.95E-05	0.0332
Glycolysis/Gluconeogenesis	6	GCK, ADH4, HK3, ENO3, ALDH3B2, PCK1	9.0593	4.56E-04	0.5119
Glycine, serine and threonine metabolism	5	CTH, SDS, AGXT2, CBS, GLDC	12.9695	5.23E-04	0.5865

FDR: false discovery rate.